another one of the great sessions at TechEd presented by Joel Oleson, Shane Young and Todd Klindt.
Again, the slides are attached to this post.
What I remembered of this session and what you also should remember:
Installation: never, never, never, really never choose Basic installation. Go for Advanced and select complete installation.
Think about SQL mirroring.
high performance (great for geographically separated SQL boxes over a WAN)
high availibility: replication between 2 SQL boxes and 1 witness server ( -> this can be a free SQL Express box!)
Find the grade of customisation to your environment by looking at the foreign DLL file references in the web.config file
App Pool Settings:
increase the startup limit
disable auto rapid fail.